Table 4 Pooled relative risk of secondary outcomes based on combined direct and indirect evidence from Bayesian network meta-analysis with different prophylaxis antifungal agents against IFIs among patients at high risk

0.65 (0.37–1.07)

0.55 (0.12–1.47)

1.08 (0.76–1.43)

2.37 (0.98–5.08)

1.41 (0.65–3.13)

0.08 (0.01–0.27)

26.57 (0.17–68.36)

0.35 (0.08–0.96)

1.55 (0.34–4.36)

1.47 (0.53–3.15)

0.45 (0.13–1.07)

202.6 (0.18–42.07)

0.78 (0.42–1.32)

3.78 (0.96–11.32)

2.19 (0.83–5.18)

1.16 (0.39–2.55)

0.87 (0.08–2.71)

1.05 (0.66–1.53)

4.15 (1.20–12.08)

0.95 (0.53–1.78)

0.73 (0.10–2.47)

20.85 (0.02–12.12)

1.03 (0.24–2.83)

1.37 (0.11–5.42)

1.89 (0.40–5.38)

1.27 (0.25–3.94)

1.41 (0.00–8.44)

0.84 (0.34–1.85)

0.12 (0.00–0.61)

2.53 (0.81, 5.80)

1.36 (0.60–2.66)

3.30 (0.77–8.54)

1.17 (0.81–1.6)

0.02 (0.00–0.03)

1.01 (0.55–2.02)

0.13 (0.01–0.44)

254.7 (0.34–210.7)

0.33 (0.07–0.94)

0.73 (0.14–2.21)

1.24 (0.28–3.03)

0.72 (0.20–1.75)

508.9 (0.38–122.2)

0.73 (0.43–1.17)

1.75 (0.42–5.19)

1.58 (0.77–2.79)

1.88 (0.59–4.28)

2.14 (0.18–7.41)

0.99 (0.62–1.49)

1.91 (0.53–5.66)

0.73 (0.37–1.25)

1.17 (0.16–4.04)

256.1 (0.07–23.31)

0.96 (0.23–2.59)

0.70 (0.04–2.90)

1.20 (0.37–2.94)

2.12 (0.36–6.92)

6.64 (0.01–22.84)

0.80 (0.29–1.86)

0.06 (0.00–0.29)

2.12 (0.43–5.55)

2.18 (0.94–4.36)

8.27 (1.51–26.57)

1.11 (0.73–1.59)

0.01 (0.00–0.02)

0.77 (0.42–1.34)

15.07 (1.09–76.67)

189.5 (0.02–46.78)

3.34 (0.67–10.58)

3.77 (0.49–14.80)

1.88 (0.44–5.71)

38.32 (2.97–184.9)

0.94 (0.00–5.56)

4.49 (1.04–13.86)

4.38 (0.61–16.00)

0.81 (0.25–2.23)

24.43 (0.98–139.1)

6.18 (0.00–11.56)

4.34 (0.54–16.84)

1.59 (0.06–6.46)

1.73 (0.23–5.55)

41.39 (2.43–212.8)

0.73 (0.00–4.27)

3.23 (0.85–9.95)

0.07 (0.00– –0.37)

1.89 (0.65–4.35)

44.78 (4.08–218.0)

3.67 (0.03–19.83)

4.98 (1.16–15.28)

0.02 (0.00–0.03)

0.86 (0.27–2.47)

3.42 (0.66–10.49)

1.30 (0.01–4.60)

1.45 (0.71–2.56)

1.35 (0.36–3.87)

0.50 (0.22–1.01)

2.19 (0.20–9.42)

5.68 (0.00–11.71)

1.41 (0.31–3.99)

0.53 (0.02–2.33)

0.85 (0.21–2.45)

3.95 (0.47–14.71)

1.89 (0.00–7.79)

1.18 (0.37–2.91)

0.05 (0.00–0.23)

1.47 (0.27–4.18)

3.99 (0.97–1.77)

3.81 (0.05–17.34)

1.62 (0.82–2.84)

0.005 (0.00–0.01)

0.54 (0.23–1.14)

0.79 (0.08–3.19)

60.34 (0.04–32.83)

1.02 (0.23–3.09)

0.51 (0.02–1.91)

1.89 (0.46–4.99)

1.41 (0.19–5.25)

6.90 (0.01–21.80)

0.84 (0.30–1.96)

0.04 (0.00–0.19)

2.95 (0.71–7.23)

1.45 (0.39–4.01)

8.07 (0.83–33.43)

1.15 (0.71–1.77)

0.004 (0.00–0.01)

1.10 (0.65–1.83)

3.43 (0.23–15.46)

38.0 (0.00–45.54)

1.21 (0.20–4.19)

0.66 (0.00–1.35)

2.43 (0.28–7.80)

3.56 (0.44–13.41)

185.0 (0.19–117.2)

1.66 (0.39–4.83)

0.05 (0.00–0.42)

0.87 (0.22–2.37)

1.79 (0.27–5.89)

435.6 (0.27–743.0)

1.67 (0.59–3.60)

1.39 (0.00–1.52)

0.53 (0.15–1.60)