Table 5 Univariate and multivariate analyses for overall survival of patients with triple-negative breast cancer
Factor | HR | Univariate analysis | P-value | HR | Multivariate analysis | P-value |
|---|---|---|---|---|---|---|
95% CI | 95% CI | |||||
Tumor size (mm) | ||||||
20 < vs ≦ 20 | 1.801 | 0.599–5.419 | 0.295 | |||
Lymph node status | ||||||
positive vs negative | 9.412 | 2.465–35.94 | 0.001 | 12.56 | 2.465–63.99 | 0.002 |
Lymphatic invasion | ||||||
positive vs negative | 1.206 | 0.155–9.402 | 0.858 | |||
Venous invasion | ||||||
positive vs negative | 3.294 | 0.733–14.80 | 0.120 | |||
Nottingham histological grade | ||||||
3 vs 1 + 2 | 2.015 | 0.672–6.035 | 0.211 | |||
Ki-67 labeling index (LI) | ||||||
high vs low | 1.199 | 0.391–3.676 | 0.750 | |||
Stromal TILs | ||||||
LPBC vs. non-LPBC | 0.300 | 0.067–1.352 | 0.117 | |||
PD-L1 expression on stromal TILs | ||||||
positive vs. negative | 0.547 | 0.190–1.579 | 0.265 | |||
Adjuvant chemotherapy | ||||||
not perform vs perform | 4.276 | 1.307–13.99 | 0.016 | 20.27 | 3.041–153.1 | 0.002 |
PD-L1 expression on CAFs | ||||||
positive vs. negative | 0.297 | 0.093–0.948 | 0.040 | 0.198 | 0.044–0.891 | 0.035 |