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Table 2 Comparison of clinicopathological features between the PD and the MD groups

From: Comparison of clinicopathological features and long-term prognosis between mixed predominantly differentiated-type and pure differentiated-type early gastric cancer

Ā 

PD group

MD group

p-value

n

409 (%)

50 (%)

Ā 

Age (years)

Meanā€‰Ā±ā€‰SD (range)

72.1ā€‰Ā±ā€‰8.6 (45ā€“91)

69.7ā€‰Ā±ā€‰10.0 (38ā€“86)

0.136

Sex

ā€ƒMale

313 (76.5%)

38 (76.0%)

0.934

ā€ƒFemale

96 (23.5%)

12 (24.0%)

Ā 

Main component

ā€ƒWell differentiated

331 (80.9)

17 (34.0)

<ā€‰0.01

ā€ƒModerately differentiated

67 (16.4)

30 (60.0)

Ā 

ā€ƒPapillary

11 (2.7)

3 (6.0)

Ā 

Location

ā€ƒUpper third

89 (21.8)

14 (28.0)

0.251

ā€ƒMiddle third

139 (34.0)

18 (36.0)

Ā 

ā€ƒLower third

181 (44.2)

18 (36.0)

Ā 

Macroscpic type

ā€ƒElevated (I,IIa)

131 (32.0)

15 (30.0)

0.388

ā€ƒFlat (IIb)

3 (0.7)

1 (2.0)

Ā 

ā€ƒDepressed (IIc, III)

232 (56.7)

24 (48.0)

Ā 

ā€ƒComplex (elevated+depressed)

43 (10.5)

10 (20.0)

Ā 

Tumor size (mm)

ā€ƒMeanā€‰Ā±ā€‰SD (range)

20.1ā€‰Ā±ā€‰15.1 (1ā€“99)

37.3ā€‰Ā±ā€‰25.8 (4ā€“128)

<ā€‰0.01

Depth

ā€ƒMucosa

313 (76.5)

17 (34.0)

<ā€‰0.01

ā€ƒSubmucosa, <ā€‰500ā€‰Ī¼m

48 (11.7)

11 (22.0)

Ā 

ā€ƒSubmucosa, ā‰„500ā€‰Ī¼m

48 (11.7)

22 (44.0)

Ā 

Lymphatic invasion

21 (5.1)

14 (28.0)

<ā€‰0.01

Vascular invasion

15 (3.7)

9 (18.0)

<ā€‰0.01

Ulceration

53 (13.0)

13 (26.0)

<ā€‰0.01

First treatment

ā€ƒESD

369 (90.2)

27 (54.0)

<ā€‰0.01

ā€ƒGastrectomy

40 (9.8)

23 (46.0)

Ā 

Non-curative resection (for ESD)

46 (12.5)

15 (55.6)

<ā€‰0.01

LNM

6 (1.5)

5 (10.0)

<ā€‰0.01

  1. Abbreviations: PD pure differentiated-type, MD mixed differentiated-type, SD standard deviation, ESD endoscopic submucosal dissection, LNM lymph node metastasis