Fig. 1
From: FOXD1 regulates cell division in clear cell renal cell carcinoma
FOXD1 expression in ccRCC. a Kaplan-Meier survival analysis for ccRCC patients with high versus low tumor expression of FOXD1 based on transcriptome data from The Cancer Genome Atlas (TCGA). High and low expression were plotted relative to median expression of FOXD1. *p = 6.85E-05. b-e FOXD1 expression in ccRCC tumors. Representative examples of tumors with mosaic nuclear staining b and ubiquitous nuclear staining c. Black arrows indicate positive and red arrow indicates negative nuclei. d Scoring of percentage nuclear staining in 142 resected ccRCC tumors. For each tumor, five high power fields were scored for percentage of positive nuclei. e The median percentage of FOXD1-positive nuclei in tumors is 58.15% (95% CI 50.6 to 65.7)