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Table 4 The performance of each risk factor to predict ipsi-LLNM in patients with PTC

From: Prediction of ipsilateral lateral cervical lymph node metastasis in papillary thyroid carcinoma: a combined dual-energy CT and thyroid function indicators study

Parameters

Cutoff value

AUC (95%CI)

Sensitivity (%)

Specificity (%)

PPV (%)

NPV (%)

P Value

Tg (ng/mL)

> 100.01

0.856 (0.818, 0.889)

76.56 (68.3, 83.6)

88.85 (84.5, 92.3)

76.0 (69.1, 81.7)

89.2 (85.7, 91.9)

< .0001

Anti-Tg (IU/mL)

> 89.43

0.766 (0.721, 0.806)

71.09 (62.4, 78.8)

86.33 (81.7, 90.1)

70.5 (63.6, 76.7)

86.6 (83.1, 89.5)

< .0001

IC IAP (mg/mL)

>  3.4

0.846 (0.807, 0.879)

72.66 (64.1, 80.2)

85.97 (81.3, 89.8)

70.5 (63.6. 76.5)

87.2 (83.7, 90.1)

< .0001

IC IVP (mg/mL)

>  3.1

0.777 (0.733, 0.816)

53.91 (44.9, 62.8)

91.37 (87.4, 94.4)

74.2 (65.5, 81.3)

81.2 (78.1, 83.9)

< .0001

ETE

N/A

0.713 (0.667, 0.757)

66.41 (57.5, 74.5)

76.26 (70.8, 81.1)

56.3 (50.2, 62.2)

83.1 (79.3, 86.4)

< .0001

  1. * Data in parentheses are 95% confidence intervals (CIs)
  2. LLNM Lateral cervical lymph node metastasis, PTC Papillary thyroid carcinoma, AUC Area under the curve, PPV Positive predictive value, NPV Negative predictive value, IC Iodine concentration, IAP In the arterial phase, IVP In the venous phase, ETE Extrathyroidal extension