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Table 4 Health service resource use during osimertinib treatment

From: Osimertinib in advanced EGFR-T790M mutation-positive non-small cell lung cancer patients treated within the Special Use Medication Program in Spain: OSIREX-Spanish Lung Cancer Group

 

Sum

Main

DT

Median

Minim

Maxim

Patients

HOSPITAL CARE health resources (n = 155)

  R01: Hospital visits/admissions (number)

1421

9.2

14.0

1

0

73

  R02: Visits to the Medical Oncologist (number)

2011

13.0

10.0

11

0

56

  R03: Visits to other hospital Physician (number)

478

3.1

5.5

1

0

48

  R04: Visits to the Hospital Nurse (number)

560

3.6

6.5

0

0

39

  R05: Emergency room visits (without admission) (n.)

143

0.9

1.6

0

0

9

  R06: Hospitalization in the emergency room (days)

54

0.3

1.0

0

0

6

  R07: Hospitalization in ward (days)

759

4.9

14.6

0

0

133

IMAGING TESTS (n = 155)

  R08: Chest x-ray (number)

333

2.1

3.1

1

0

16

  R09: CT scan (number)

475

3.1

2.5

3

0

12

  R10: Magnetic resonance (number)

113

0.7

1.3

0

0

6

  R11: Endobronchial ultrasound (number)

2

0.0

0.2

0

0

2

  R12: Esophageal Endoscopic Ultrasound (number)

2

0.0

0.2

0

0

2

  R13: Other tests (number)

65

0.4

1.2

0

0

10

OTHER complementary tests (n = 155)

  R14: Bone scintigraphy (number)

32

0.2

0.6

0

0

3

  R15: Sputum cytology (number)

1

0.0

0.1

0

0

1

  R16: Thoracentesis (number)

12

0.1

0.3

0

0

3

  R17: Biopsy (number)

64

0.4

1.5

0

0

9

  R18: Bronchoscopy (number)

12

0.1

0.4

0

0

4

  R19: Mediastinoscopy (number)

0

  R20: Mediastinotomy (number)

0

  R21: Thoracoscopy (number)

0

  R22: Spirometry (number)

5

0.0

0.2

0

0

1

  R23: Plethysmography (number)

0

  R24: Electrocardiogram (number)

198

1.3

3.6

0

0

30

  R25: Other tests (number)

18

0.1

0.4

0

0

4

PRIMARY CARE health resources (n = 152)

  R26: Visits to primary care (number)

271

1.8

5.4

0

0

39

  R27: Visits to primary care Physician (number)

257

1.7

5.0

0

0

36

  R28: Visits to primary care Nurse (number)

166

1.1

5.1

0

0

37

  R29: Tests performed (number)

112

0.7

4.8

0

0

50

  R30: Chest x-ray (number)

20

0.1

0.9

0

0

10

  R31: Complete blood count (number)

224

1.5

6.0

0

0

50

  R32: Other tests (number)

6

0.0

0.3

0

0

3

LABORATORY TESTS (n = 155)

  R33: Immunohistochemistry (number)

35

0.2

1.3

0

0

15

  R34: Molecular tests (EGFR, ALK, ROS1, BRAF) (num.)

66

0.4

1.0

0

0

5

  R35: Complete blood count (number)

1.873

12.1

10.5

9

0

62

  R36: Blood chemistry (number)

1.859

12.0

10.4

9

0

62

  R37: Proteins in urine (number)

310

2.0

6.3

0

0

35

  R38: Other tests (number)

119

0.8

3.2

0

0

29

SURGERIES (n = 155)

  R39: Pneumectomy (number)

0

  R40: Lobectomy (number)

0

  R41: Segmentation or wedge resection (number)

0

  R42: Sleeve resection (number)

0

  R43: Others (number)

5

0.0

0.2

0

0

2

OTHER RESOURCES/SUPPORT (n = 155)

  R44: Radiofrequency ablation (number)

1

0.0

0.1

0

0

1

  R45: Radiotherapy palliative (number of sessions)

159

1.0

4.0

0

0

40

  R46: Pleurodesis (number)

1

0.0

0.1

0

0

1

  R47: Corticosteroids

no

117

75.5%

yes

38

24.5%

  R48: Bisphosphonates

no

142

91.6%

yes

13

8.4%

  R49: Stimulants of erythropoietin

no

151

97.4%

yes

4

2.6%

  R50: Blood transfusions

no

147

94.8%

yes

8

5.2%

  R51: Enteral nutrition

no

153

98.7%

yes

2

1.3%

  R52: Others

no

145

93.5%

yes

10

6.5%