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Table 1 Patient clinical characteristics

From: Osimertinib in advanced EGFR-T790M mutation-positive non-small cell lung cancer patients treated within the Special Use Medication Program in Spain: OSIREX-Spanish Lung Cancer Group

 

Total

Patients

155 (100%)

Sex

 Male

47 (30.3%)

 Female

108 (69.7%)

Age

 Mean (SD)

66.9 (11.4)

 Median (Min.-Max.)

67 (37–88)

Race

 Caucasian

149 (96.2%)

 Latin

5 (3.2%)

 African

1 (0.6%)

Smoking habit

 Non-smoker (≤100 cigarettes over lifetime)

99 (63.9%)

 Former smoker (≥1 year)

41 (26.5%)

 Smoker

14 (9.0%)

 Not provided

1 (0.6%)

Performance Status (PS)

 0

43 (27.7%)

 1

75 (48.4%)

 2

10 (6.5%)

 3

3 (1.9%)

 Not reported

24 (15.5%)

Histology

 Adenocarcinoma

154 (99.4%)

 Undifferentiated

1 (0.6%)

M staging

 MX

1 (0.6%)

 M0

27 (17.5%)

 M1

127 (81.9%)

Metastatic sites

 Extra-thoracic adenopathy

16 (10.3%)

 Thoracic adenopathy

40 (25.8%)

 Meningeal carcinomatosis

2 (1.3%)

 Pericardial effusion

7 (4.5%)

 Pleural effusion

46 (29.7%)

 Liver

19 (12.3%)

 Bones

59 (38.1%)

 Bilateral lymphangitis

7 (4.5%)

 Pleural nodes

29 (18.7%)

 Peritoneal

4 (2.6%)

 Lung

79 (51.0%)

 Central nervous system

22 (14.2%)

 Subcutaneous

1 (0.6%)

 Suprarenal

9 (5.8%)

 Soft tissue

2 (1.3%)

 Choroids

2 (1.3%)