Fig. 4

Recommender system results. a Graph representation of 100 rules with highest lift values; vertices represent drugs and are colored to reflect drug target classification as specified in the legend. Edges indicate the rule-governed relationships between them, colored based on the type of relationship. b Matrix plot of all discovered rules that met the 0.2 support and 0.8 confidence cutoff criteria. Squares are colored by combination of confidence and support values with more red representing higher confidence in the association, with blue representing higher support for the association. Axis labels were colored to help identify drug relationships: dark red corresponding to “resistant” and grey corresponding to “sensitive”. In addition, “_sens” and “_res” types of relationships were appended to the drug names in axis labels and correspond to “sensitive” and “resistant” respectively