Table 4 Treatment-Related Toxicities
Adverse Event | Grade1 n(%) | Grade2 n(%) | Grade3 n(%) | Grade4 n(%) | Total n(%) |
|---|---|---|---|---|---|
Monotherapy group(n = 12) | |||||
Secondary hypertension | 1 (8.3) | 2 (16.7) | 1 (8.3) | 1 (8.3) | 5 (41.7) |
Hand-foot syndrome | 1 (8.3) | 1 (8.3) | 1 (8.3) | 0 | 3 (25.0) |
Proteinuria | 2 (16.7) | 0 | 0 | 0 | 2 (16.7) |
Fatigue | 1 (8.3) | 2 (16.7) | 0 | 0 | 3 (25.0) |
Diarrhea | 1 (8.3) | 0 | 0 | 0 | 1 (8.3) |
Combination group(n = 16) | |||||
Secondary hypertension | 2 (12.5) | 1 (6.3) | 0 | 0 | 3 (18.8) |
Hand-foot syndrome | 1 (6.3) | 2 (12.5) | 0 | 0 | 3 (18.8) |
Proteinuria | 2 (12.5) | 0 | 0 | 0 | 2 (12.5) |
Nausea | 2 (12.5) | 2 (12.5) | 0 | 0 | 4 (25.0) |
Neutropenia | 5 (31.3) | 1 (6.3) | 1 (6.3) | 0 | 7 (43.8) |