Table 7 Prediction of the effect of the non-synonymous mutation on protein structure and function
From: Mutational profiles of marker genes of cervical carcinoma in Bangladeshi patients
Gene | Mutation | Type | Position (Chromosome) | SIFT Score | PolyPhen Score |
|---|---|---|---|---|---|
EGFR | G > A | Exonic | Chr7 55,170,575 | 0.5 (tolerated) | 0 (benign) |
PIK3CA | T > A | Exonic | Chr3 179,218,237 | 0.26 (tolerated low confidence) | 0.001 (benign) |