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Fig. 3 | BMC Cancer

Fig. 3

From: Blockage of AMPK-ULK1 pathway mediated autophagy promotes cell apoptosis to increase doxorubicin sensitivity in breast cancer (BC) cells: an in vitro study

Fig. 3

Inhibition of autophagy by 3-MA aggravated the promoting effects of high-dose doxorubicin-induced cell death in DR-BC cells. a, b Cell proliferation was evaluated by CCK-8 assay. c, d Colonies formation abilities were examined by colony formation assay. e Trypan blue staining assay was performed to determine cell viability. f, g Cell apoptosis was determined by using the Annexin V-FITC/PI double staining method. Each experiment repeated at least 3 times, and *P < 0.05 was regarded as statistical significance

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