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Fig. 3 | BMC Cancer

Fig. 3

From: Super-enhancer-associated long noncoding RNA AC005592.2 promotes tumor progression by regulating OLFM4 in colorectal cancer

Fig. 3

Knockdown of AC005592.2 inhibited CRC cell proliferation, invasion, and migration and induced apoptosis. a Relative expression of AC005592.2 in HCT-116 and HT-29 cells after transfection with AC005592.2 siRNAs. b CCK-8 assays revealed that AC005592.2 knockdown significantly inhibited HCT-116 and HT-29 cells proliferation. c Transwell assays revealed that AC005592.2 knockdown significantly inhibited migration and invasion of HCT-116 and HT-29 cells. d Apoptosis assays by flow cytometry indicated that AC005592.2 knockdown increased the apoptosis rate of HCT-116 and HT-29 cells. * P-value < 0.05, ** P-value < 0.01

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BMC Cancer

ISSN: 1471-2407

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