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Table 4 Difference in clinical features between iC1 subtype and iC2 subtype for LUAD

From: Multi-omics analysis of genomics, epigenomics and transcriptomics for molecular subtypes and core genes for lung adenocarcinoma

Variables

iC1 (n = 183)

iC2 (n = 257)

P

Age (median [IQR])

63.50 [58.00, 72.00]

67.00 [59.00, 74.00]

0.068

Gender (%)

 Female

86 (47.0)

149 (58.0)

0.026*

 Male

97 (53.0)

108 (42.0)

 

Status (%)

 Dead

97 (53.0)

185 (72.0)

< 0.001***

 Alive

86 (47.0)

72 (28.0)

 

Pathologic T (%)

 T1

53 (29.0)

99 (38.5)

0.293

 T2

105 (57.4)

126 (49.0)

 

 T3

17 (9.3)

22 (8.6)

 

 T4

7 (3.8)

9 (3.5)

 

 Tx

1 (0.5)

1 (0.4)

 

Pathologic N (%)

 N0

103 (56.3)

186 (72.7)

< 0.001***

 N1

44 (24.0)

36 (14.1)

 

 N2

34 (18.6)

28 (10.9)

 

 N3

1 (0.5)

0 (0.0)

 

 NX

1 (0.5)

6 (2.3)

 

Pathologic M (%)

  

0.251

 M0

121 (66.5)

157 (61.8)

 

 M1

10 (5.5)

9 (3.5)

 

 Mx

51 (28.0)

88 (34.6)

 

Tumor stage (%)

  

< 0.001***

 I

79 (43.4)

159 (62.8)

 

 II

57 (31.3)

51 (20.2)

 

 III

36 (19.8)

34 (13.4)

 

 IV

10 (5.5)

9 (3.6)

 
  1. *P < 0.05; ***P < 0.001