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Table 1 Features of 12 articles included in this meta-analysis

From: The relationship between the expression of Ki-67 and the prognosis of osteosarcoma

REF First author Year Cases Gender
(M/F)
Median age Inclusion period Method ki-67 cut-off Ethnicity NOS score
1 Wang et al. 2018 50 28/22 24.15 2015–2017 IHC A1*B1 > 3 Asian 8
2 Fu et al. 2017 20 9/11 11.27 2008–2012 IHC A1 ≥ 1 Asian 8
3 Li et al. 2017 21 11/10 24.33 2011–2013 IHC A1 ≥ 1 Asian 8
4 Lin et al. 2014 55 31/24 17.42 2004–2011 IHC A1*B2 > 3 Asian 7
5 Li et al. 2014 94 59/35 2006–2010 IHC B3 ≥ 2 Asian 7
6 Matsumoto et al. 2013 29 19/10 19.00 1978–2007 IHC A1 ≥ 1 Asian 8
7 Junior et al 2003 25 13/12 29.00 1958–2001 IHC A1 ≥ 1 Asian 8
8 Xu et al. 2003 30 16/14 19.83 IHC A3 ≥ 2 Asian 7
9 Zhang et al. 2003 30 16/14 1994–1999 IHC A3 ≥ 2 Asian 7
10 Peng et al. 2002 62 17.00 1995–2001 IHC A1 ≥ 1 Asian 8
11 Zhang et al. 2001 45 28/17 17.60 1993–1998 IHC A1 ≥ 1 Asian 8
12 Liao et al. 1998 39 26/13 20.10 1992–1995 IHC A1 ≥ 1 Asian 7
  1. A: Positive cell percentage: A1: scored 0 (< 5%), 1 (6–25%), 2 (26–50%), 3 (> 50%); A2: scored 1 (< 25%), 2 (26–50%), 3 (51–75%), 4 (> 75%); A3: scored 0 (< 5%), 1 (5–20%), 2 (> 20%)
  2. B: Staining intensity: B1: scored 0 (light yellow), 1 (brownish yellow), 2 (brown); B2: scored 0 (absence of staining), 1 (weak staining), 2 (middle staining), 3 (strong staining); B3: scored 0 (absence of staining), 1 (light yellow), 2 (brownish yellow), 3 (brown)