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Table 1 Features of 12 articles included in this meta-analysis

From: The relationship between the expression of Ki-67 and the prognosis of osteosarcoma

REF

First author

Year

Cases

Gender

(M/F)

Median age

Inclusion period

Method

ki-67 cut-off

Ethnicity

NOS score

1

Wang et al.

2018

50

28/22

24.15

2015–2017

IHC

A1*B1 > 3

Asian

8

2

Fu et al.

2017

20

9/11

11.27

2008–2012

IHC

A1 ≥ 1

Asian

8

3

Li et al.

2017

21

11/10

24.33

2011–2013

IHC

A1 ≥ 1

Asian

8

4

Lin et al.

2014

55

31/24

17.42

2004–2011

IHC

A1*B2 > 3

Asian

7

5

Li et al.

2014

94

59/35

2006–2010

IHC

B3 ≥ 2

Asian

7

6

Matsumoto et al.

2013

29

19/10

19.00

1978–2007

IHC

A1 ≥ 1

Asian

8

7

Junior et al

2003

25

13/12

29.00

1958–2001

IHC

A1 ≥ 1

Asian

8

8

Xu et al.

2003

30

16/14

19.83

IHC

A3 ≥ 2

Asian

7

9

Zhang et al.

2003

30

16/14

1994–1999

IHC

A3 ≥ 2

Asian

7

10

Peng et al.

2002

62

17.00

1995–2001

IHC

A1 ≥ 1

Asian

8

11

Zhang et al.

2001

45

28/17

17.60

1993–1998

IHC

A1 ≥ 1

Asian

8

12

Liao et al.

1998

39

26/13

20.10

1992–1995

IHC

A1 ≥ 1

Asian

7

  1. A: Positive cell percentage: A1: scored 0 (< 5%), 1 (6–25%), 2 (26–50%), 3 (> 50%); A2: scored 1 (< 25%), 2 (26–50%), 3 (51–75%), 4 (> 75%); A3: scored 0 (< 5%), 1 (5–20%), 2 (> 20%)
  2. B: Staining intensity: B1: scored 0 (light yellow), 1 (brownish yellow), 2 (brown); B2: scored 0 (absence of staining), 1 (weak staining), 2 (middle staining), 3 (strong staining); B3: scored 0 (absence of staining), 1 (light yellow), 2 (brownish yellow), 3 (brown)