Table 2 Univariable and multivariable Cox regression analyses of OS
Univariable | Multivariable | |||||
|---|---|---|---|---|---|---|
HR | 95% CI | P | HR | 95% CI | P | |
Age | 1.01 | (0.99,1.02) | 0.308 | |||
BMI | 0.98 | (0.94,1.03) | 0.418 | |||
Blood glucose | ||||||
Normal | ref | |||||
Abnormal | 1.08 | (0.82,1.44) | 0.574 | 1.04 | (0.78,1.4) | 0.781 |
Sex | ||||||
Female | ref | |||||
Male | 1.07 | (0.81,1.41) | 0.621 | |||
Smoking history | ||||||
No | ref | |||||
Yes | 1.14 | (0.86,1.51) | 0.358 | |||
Drinking history | ||||||
No | ref | |||||
Yes | 1.30 | (0.94,1.81) | 0.113 | |||
Diabetes | ||||||
No | ref | |||||
Yes | 1.05 | (0.77,1.43) | 0.771 | |||
Hypertension | ||||||
No | ref | |||||
Yes | 0.94 | (0.69,1.27) | 0.683 | |||
Allergic history | ||||||
No | ref | |||||
Yes | 1.22 | (0.83,1.78) | 0.314 | |||
Abdominal pain | ||||||
No | ref | |||||
Yes | 1.08 | (0.8,1.47) | 0.607 | |||
Back pain | ||||||
No | ref | |||||
Yes | 0.61 | (0.4,0.92) | 0.019 | 0.65 | (0.42,1.03) | 0.064 |
Anorexia | ||||||
No | ref | |||||
Yes | 0.86 | (0.4,1.82) | 0.689 | |||
Loss of appetite | ||||||
No | ref | |||||
Yes | 1.09 | (0.82,1.43) | 0.559 | |||
Loss of weight | ||||||
No | ref | |||||
Yes | 0.82 | (0.62,1.09) | 0.165 | |||
CA199 | ||||||
Normal | ref | |||||
37–1000 | 1.47 | (1.02,2.12) | 0.039 | 1.38 | (0.94,2.01) | 0.099 |
> 1000 | 1.84 | (1.14,2.97) | 0.013 | 1.86 | (1.15,3.02) | 0.012 |
Surgical procedure | ||||||
Whipple | ref | |||||
Distal | 1.26 | (0.91,1.75) | 0.161 | |||
Other | 0.95 | (0.44,2.02) | 0.886 | |||
Location | ||||||
Head | ref | |||||
Tail | 1.21 | (0.87,1.69) | 0.253 | |||
Differentiation degree | ||||||
Poor | ref | |||||
Moderate-high | 0.79 | (0.57,1.08) | 0.144 | |||
AJCC8 staging | ||||||
Stage I | ref | |||||
Stage II | 1.05 | (0.77,1.43) | 0.753 | |||
Stage III-IV | 1.30 | (0.9,1.87) | 0.162 | |||
Obstructive jaundice | ||||||
No | ref | |||||
Yes | 0.89 | (0.68,1.17) | 0.405 | |||