Table 1 Clinicopathologic features of study group patients
Clinical and pathologic features | CAC (N [%]) | Sporadic CRCs (N [%]) | p |
|---|---|---|---|
No. of Cases | 30 | 10 | |
Sex, male/female | 19 / 11 | 5 / 5 | 0.482 |
Median age (range) (y) | 54 (26–76) | 67 (40–95) | 0.017 |
Location | |||
colon | 22 (73) | 8 (80) | 1 |
rectum | 8 (27) | 2 (20) | |
pT stage | |||
1 | 8 (27) | 1 (10) | 0.144 |
2 | 4 (13) | 2 (20) | |
3 | 15 (50) | 3 (30) | |
4 | 3 (10) | 4 (40) | |
pN stage | |||
0 | 16 (53) | 5 (50) | 1 |
1 or 2 | 14 (47) | 5 (50) | |
Cancer subtypes | |||
Conventional | 12 (40) | 8 (80) | 0.243 |
Mucinous | 9 (30) | 1 (10) | |
Serrated | 3 (10) | 1 (10) | |
LGTG | 5 (17) | 0 (0) | |
Other | 1 (3) | 0 (0) | |
LGR5 | |||
Positive | 9 (30) | 9 (90) | 0.002 |
(Score 3) | 6 (20) | 3 (30) | |
(Score 4) | 3 (10) | 6 (60) | |
Negative | 21 (70) | 1 (10) | |
(Score 0) | 2 (7) | 0 (0) | |
(Score 1) | 9 (30) | 0 (0) | |
(Score 2) | 10 (33) | 1 (10) | |