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Fig. 7 | BMC Cancer

Fig. 7

From: Diallyl thiosulfinate enhanced the anti-cancer activity of dexamethasone in the side population cells of multiple myeloma by promoting miR-127-3p and deactivating the PI3K/AKT signaling pathway

Fig. 7

Silencing miR-127-3p expression reversed effect of cotreatment with diallyl thiosulfinate and dexamethasone (DATS+Dex) on the apoptosis, colony formation, cell cycle, and spheroids formation of multiple myeloma (MM) side population (SP) cells. Silencing miR-127-3p expression a inhibited apoptosis, b promoted colony formation, and c promoted cell cycle progression of MM SP cells treated with DATS+Dex. d Representative image of spheroids formation by SP cells after treatment with DATS, Dex, or DATS+Dex (magnification, × 100). ***P < 0.001

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BMC Cancer

ISSN: 1471-2407

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