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Fig. 2 | BMC Cancer

Fig. 2

From: Diallyl thiosulfinate enhanced the anti-cancer activity of dexamethasone in the side population cells of multiple myeloma by promoting miR-127-3p and deactivating the PI3K/AKT signaling pathway

Fig. 2

Diallyl thiosulfinate and dexamethasone (DATS+Dex) cotreatment inhibited proliferation and colony formation of multiple myeloma (MM) side population (SP) cells. a Effect of DATS, Dex, and DATS+Dex treatments on proliferation of MM SP cells detected using MTS analysis at 0, 24, 48, 72 h after treatment. b Bar represents cell numbers of colonies formed in SP cells after treatment with DATS, Dex, or DATS+Dex. c Representative image of colony formation by SP cells after treatment with DATS, Dex, or DATS+Dex. d Representative image of spheroids formation by SP cells after treatment with DATS, Dex, or DATS+Dex (magnification, × 100). ***P < 0.001 vs normal group, &P < 0.05 and &&&P < 0.001 vs DATS group, and ###P < 0.001 vs Dex

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BMC Cancer

ISSN: 1471-2407

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