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Table 2 Multivariate Cox regression for OS and LCSS

From: Development and validation of a nomogram for predicting survival of pulmonary invasive mucinous adenocarcinoma based on surveillance, epidemiology, and end results (SEER) database

Characteristics

OS

LCSS

HR

95.0%CI

p

HR

95.0%CI

p

Gender

 Female

1

 

1

 

 Male

1.223

0.934–1.601

0.143

1.091

0.793–1.503

0.592

Age

 ≤ 59

1

 

1

 

 60–69

1.830

1.223–2.740

0.003

1.742

1.097–2.768

0.019

 70–79

2.646

1.813–3.862

< 0.001

2.312

1.493–3.581

< 0.001

 ≥ 80

4.121

2.555–6.648

< 0.001

3.007

1.695–5.336

< 0.001

Laterality

 Only one side

1

 

1

 

 Bilateral

0.994

0.386–2.562

0.991

1.074

0.408–2.827

0.886

Grade

 Well differentiated

1

 

   

 Moderately differentiated

1.118

0.787–1.586

0.534

1.003

0.661–1.522

0.989

 Poorly differentiated/Undifferentiated

2.569

1.483–4.450

< 0.001

2.793

1.531–5.093

< 0.001

Tstage_8th

 T1

1

 

1

 

 T2

1.214

0.828–1.778

0.320

1.351

0.819–2.229

0.238

 T3

1.633

1.051–2.538

0.029

2.063

1.193–3.566

0.010

 T4

2.925

1.996–4.287

< 0.001

4.298

2.671–6.917

< 0.001

Nstage_8th

 N0

1

 

1

 

 N1

1.756

1.044–2.954

0.034

1.936

1.100–3.409

0.022

 N2/3

2.232

1.337–3.726

0.002

2.524

1.465–4.348

< 0.001

Mstage_8th

 M0

1

 

1

 

 M1

2.278

1.436–3.612

< 0.001

2.202

1.327–3.653

0.002

Surgery

 No

1

 

1

 

 Yes

0.467

0.305–0.715

< 0.001

0.452

0.277–0.737

0.001

Radiation

 No

1

 

1

 

 Yes

1.991

1.149–3.449

0.001

1.931

1.061–3.514

0.031

Chemotherapy

 No/Unknown

1

 

1

 

 Yes

1.492

1.062–2.096

0.021

1.730

1.193–2.509

0.004