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Table 1 Patient Baseline Characteristics

From: One year of procarbazine lomustine and vincristine is poorly tolerated in low grade glioma: a real world experience in a national neuro-oncology centre

  Age < 40
N = 20
Age ≥ 40
N = 21
Total
N = 41
(%)
p-value
N % N % N %
Sex:        0.412a
 Male 13 65 11 52 24 58  
 Female 7 35 10 48 17 41  
Recurrent/First Diagnosis:        0.427a
 First Diagnosis 12 60 10 48 22 54  
 Recurrent 8 40 11 52 19 46  
Surgery:        1.00b
 Resection 18 90 20 95 38 93  
 Biopsy 2 10 1 5 3 7  
Histology:        0.002a
 Oligodendroglioma 9 45 19 90 28 68  
 Astrocytoma 11 55 2 9 13 32  
IDH:        1.00b
 Mutated 19 95 19 90 38 93  
 Wildtype 0 0 0 0 0 0  
 Unknown 1 5 2 9 3 7  
1p19q Co-deletion:        0.001a
 Present 7 35 18 86 25 61  
 Absent 10 50 2 9 12 29  
 Unknown 3 15 1 5 4 10  
MGMT
 Methylated 8 40 6 29 14 34  
 Unmethylated 1 5 0 0 1 2.4  
 Unknown 11 55 15 71 26 63  
ATRX
 Mutated 5 25 1 5 6 15  
 Wildtype 3 15 8 38 11 27  
 Unknown 12 60 12 57 24 58  
  1. Each value is represented by number of patients (N) and percentage of patients (%)
  2. aChi-square test for independence
  3. bFisher’s exact test