Table 3 Univariate analyses of factors associated with bone metastasis in 157 HCC patients

Age (≤56 versus > 56 years)

0.725(0.286–1.840)

0.499

Gender (male versus female)

1.864(0.539–6.445)

0.325

HBsAg (negative versus positive)

1.849(0.425–8.047)

0.412

HCV-Ab (negative versus positive)

1.707(0.227–12.838)

0.603

AFP, ng/mL (≤ 20 versus > 20)

1.612(0.574–4.526)

0.364

ALT,U/L (≤ 40 versus > 40)

0.255(0.034–1.915)

0.184

γ-GT,U/L (≤ 50 versus > 50)

1.032(0.400–2.662)

0.949

Liver cirrhosis (no versus yes)

4.662(0.620–35.039)

0.135

Child-Pugh score (A versus B)

1.155(0.153–8.697)

0.889

Tumor differentiation (I–II versus III–IV)

1.504(0.597–3.789)

0.387

Tumor size, cm (≤ 5 versus > 5)

0.657(0.216–1.996)

0.458

Tumor number (single versus multiple)

0.963(0.373–2.486)

0.937

Tumor encapsulation (complete versus none)

1.079(0.426–2.737)

0.872

Vascular invasion (no versus yes)

10.054(3.572–28.302)

< 0.001

BCLC stage (0-A versus B-C)

7.193(2.361–21.919)

0.001

Lnc34a (low versus high)

5.385(1.558–18.612)

0.008