Variable | Univariate analysis | Multivariate analysis | ||||
---|---|---|---|---|---|---|
HR | 95% CI | P | HR | 95% CI | P | |
Sex | 1.065 | 0.823–0.232 | 0.630 | |||
Age | 0.994 | 0.984–1.004 | 0.268 | |||
Somking | 1.843 | 1.257–2.703 | 0.002 | 1.651 | 1.117–2.439 | 0.012 |
Tumor history | 0.703 | 0.435–1.137 | 0.703 | |||
Obstruction | 2.456 | 1.861–3.241 | < 0.001 | 1.843 | 1.374–2.473 | < 0.001 |
Tumor size | 1.01 | 0.951–1.072 | 0.748 | |||
Tumor location | ||||||
Rectum | Reference | Reference | ||||
Right colon | 1.574 | 1.18–2.101 | 0.002 | 1.146 | 0.811–1.619 | 0.440 |
Left colon | 1.56 | 1.12–2.171 | 0.008 | 1.400 | 0.603–1.111 | 0.199 |
Differentiation | ||||||
Well | Reference | |||||
Moderate | 0.99 | 0.699–1.402 | 0.954 | |||
Poor | 0.646 | 0.322–1.296 | 0.218 | |||
T stage | ||||||
T1 | Reference | Reference | ||||
T2 | 0.875 | 0.375–2.045 | 0.758 | 0.87 | 0.368–2.058 | 0.752 |
T3 | 1.803 | 0.877–3.705 | 0.109 | 1.775 | 0.828–3.805 | 0.140 |
T4 | 5.968 | 2.915–12.219 | < 0.001 | 3.486 | 1.622–7.534 | 0.001 |
N stage | ||||||
N0 | Reference | Reference | ||||
N1 | 2.068 | 1.512–2.829 | < 0.001 | 1.311 | 0.861–1.998 | 0.207 |
N2 | 4.149 | 3.063–5.620 | < 0.001 | 2.309 | 1.539–3.466 | < 0.001 |
TNM stage | ||||||
I | Reference | Reference | ||||
II | 1.914 | 0.935–3.914 | 0.076 | 0.751 | 0.328–1.719 | 0.498 |
III | 4.312 | 2.184–8.513 | < 0.001 | 1.031 | 0.446–2.384 | 0.943 |
IV | 10.482 | 5.259–20.893 | < 0.001 | 2.588 | 1.135–5.902 | 0.024 |
Perineural invasion | 0.869 | 0.632–1.196 | 0.390 | |||
Vascular invasion | 0.952 | 0.675–1.343 | 0.781 | |||
Chemotherapy | 0.626 | 0.483–0.810 | < 0.001 | 0.579 | 0.442–0.76 | < 0.001 |
TBIL | 0.188 | 0.116–0.303 | < 0.001 | 0.436 | 0.329–0.578 | < 0.001 |
DBIL | 0.528 | 0.376–0.742 | < 0.001 | 0.435 | 0.299–0.637 | < 0.001 |
TBA | 0.26 | 0.201–0.337 | < 0.001 | 0.206 | 0.124–0.341 | < 0.001 |