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Table 3 Associations between TBA level and clinical characteristics in CRC patients

From: A nomogram based on pretreatment levels of serum bilirubin and total bile acid levels predicts survival in colorectal cancer patients

Variable

 

TBA group

Statistics

P

 

Low TBA (n), %

High TBA (n), %

Sex

Male

699 (57.6)

168 (64.4)

4.031

0.045

Femal

514 (42.4)

93 (35.6)

  

Age

 

58.11 ± 12.14

57.87 ± 12.41

0.287

0.774

Somking

Yes

246 (20.3)

57 (21.8)

0.32

0.572

No

967 (79.7)

204 (78.2)

  

Tumor history

Yes

134 (11.1)

22 (8.4)

1.555

0.212

No

1079 (88.9)

239 (91.6)

  

Obstruction

Obstruction

  

1.617

0.203

Yes

189 (15.6)

49 (18.8)

  

No

1024 (84.4)

212 (81.2)

  

Tumor size (cm)

4.22 ± 2.12

4.07 ± 1.93

1.068

0.286

Tumor location

Right colon

363 (29.9)

88 (33.7)

1.893

0.388

Left colon

234 (19.3)

52 (19.9)

  

Rectum

616 (50.8)

121 (46.4)

  

Differentiation (%)

Well

176 (14.5)

45 (17.2)

2.653

0.265

Moderate

955 (78.7)

204 (78.2)

  

Poor

82 (6.8)

12 (4.6)

  

T stage (%)

T1

92 (7.6)

16 (6.1)

6.484

0.09

T2

204 (16.8)

35 (13.4)

  

T3

650 (53.6)

135 (51.7)

  

T4

267 (22.0)

75 (28.7)

  

N stage (%)

N0

703 (58.0)

141 (54.0)

1.449

0.484

N1

305 (25.1)

70 (26.8)

  

N2

205 (16.9)

50 (19.2)

  

TNM stage (%)

I

170 (14.0)

27 (10.3)

12.202

0.007

II

418 (34.5)

84 (32.2)

  

III

481 (39.7)

99 (37.9)

  

IV

144 (11.8)

51 (19.5)

  

Perineural invasion (%)

Yes

264 (21.8)

55 (21.1)

0.061

0.806

No

949 (78.2)

206 (78.9)

  

Vascular invasion (%)

Yes

213 (17.6)

52 (19.9)

0.814

0.367

No

1000 (82.4)

209 (80.1)

  

Chemotherapy (%)

Yes

657 (54.2)

125 (47.9)

3.391

0.066

No

556 (45.8)

136 (52.1)

  
  1. TBA Total Bile Acid, CRC Colorectal Cancer