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Table 1 Patients characteristics

From: Clinical features associated with the efficacy of chemotherapy in patients with glioblastoma (GBM): a surveillance, epidemiology, and end results (SEER) analysis

Characteristic

Total, n

No chemotherapy, n

Received chemotherapy, n

p

25,698

7632

18,066

Age at diagnosis, n (%)

 Young

271 (1.05)

55 (0.72)

216 (1.20)

< 0.0001

 Adult

14,134 (55.00)

2817 (36.91)

11,317 (62.64)

 

 Old

11,293 (43.95)

4760 (62.37)

6533 (36.16)

 

Gender, n (%)

 Male

14,920 (58.06)

4119 (53.97)

10,801 (59.78)

< 0.0001

 Female

10,778 (41.94)

3513 (46.03)

7265 (40.21)

 

Race, n (%)

 White

22,963 (89.36)

6771 (88.72)

16,192 (89.63)

0.026

 Black

1438 (5.60)

462 (6.05)

976 (5.40)

 

 American indian/alaska native

109 (0.42)

24 (0.31)

85 (0.47)

 

 Asian of pacific islander

1146 (4.46)

354 (4.64)

792 (4.38)

 

    Unknown

42 (0.16)

21 (0.28)

21 (0.12)

 

Primary site, n (%)

 Supratentorial

20,170 (78.48)

5792 (75.89)

14,378 (79.59)

< 0.0001

 Infratentorial

417 (1.62)

133 (1.74)

284 (1.57)

 

 Brain overlap

3803 (14.80)

1229 (16.11)

2574 (14.25)

 

 Unknown

1308 (5.10)

478 (6.26)

830 (4.59)

 

Size, n (%)

  ≤ 4 cm

9606 (37.38)

2661 (34.87)

6945 (38.44)

< 0.0001

  > 4 cm

16,092 (62.62)

4971 (65.13)

11,121 (61.56)

 

Surgery, n (%)

 No

5219 (20.31)

2598 (34.04)

2621 (14.51)

< 0.0001

 Yes

20,436 (79.52)

5005 (65.58)

15,431 (85.41)

 

 Unknown

43 (0.17)

29 (0.38)

14 (0.08)

 

Radiation, n (%)

 No

8883 (34.57)

5692 (74.58)

3191 (17.66)

< 0.0001

 Yes

16,815 (65.43)

1940 (25.42)

14,875 (82.34)

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