Fig. 4
From: The diagnostic value of lower glucose consumption for IDH1 mutated gliomas on FDG-PET
Expression of HK1, PKM2, and PC in gliomas. Bioinformatic analysis of TCGA data shows that the mRNA of HK1 and PKM2 is higher in IDH1wt than that in IDH1mut gliomas (a, b), while PC expression is significantly higher in IDH1mut than that in IDH1wt gliomas (c). Furthermore, the up regulation of HK1 and PKM2 in IDH1wt gliomas are confirmed with western blot, while the expression of PC is higher in IDH1mut gliomas than that in IDH1wt group, the gels/blots were processed in parallel (d, full-length blots/gels are presented in Supplementary 2 Fig. [X])