Table 6 Univariate and multivariate analysis for overall survival after curative hepatectomy for propensity score-matched patients with BCLC 0/A stage HCC

Age (years)

>60 vs. ≦ 60

0.990 (0.558–1.757)

0.974

Sex

Male vs. Female

1.013 (0.455–2.253)

0.975

AFP (ng/mL)

>200 vs. ≦ 200

1.172 (0.545–2.518)

0.685

Liver cirrhosis

Yes vs. No

1.669 (0.942–2.955)

0.079

Diabetes

Yes vs. No

3.175 (1.652–6.103)

0.001

Child-Pugh grade

B vs. A

1.415 (0.601–3.330)

0.427

Tumor number

Multiple vs. Single

0.711 (0.098–5.159)

0.736

Tumor size (cm)

>2 vs. ≦ 2

4.271 (0.588–30.998)

0.151

Histology stages

poor vs. well + moderate

1.651 (0.651–4.187)

0.291

Vascular invasion

Yes vs. No

2.455 (1.367–4.409)

0.003

Statin

Yes vs. No

0.509 (0.229–1.132)

0.098

NSAID

Yes vs. No

3.305 (1.309–8.345)

0.011

Aspirin

Yes vs. No

1.021 (0.479–2.176)

0.957

Metformin

Yes vs. No

1.310 (0.669–2.566)

0.431

NA therapy

Yes vs. No

0.830 (0.425–1.622)

0.586

HCV therapy

Yes vs. No

0.440 (0.137–1.418)

0.169