Table 5 Univariate and multivariate analysis for recurrence after curative hepatectomy for propensity score-matched patients with BCLC 0/A stage HCC

Age (years)

>60 vs. ≦ 60

1.013 (0.696–1.473)

0.947

Sex

Male vs. Female

0.933 (0.557–1.561)

0.791

AFP (ng/mL)

>200 vs. ≦ 200

0.785 (0.456–1.351)

0.381

Liver cirrhosis

Yes vs. No

1.436 (0.982–2.102)

0.062

Diabetes

Yes vs. No

1.733 (1.194–2.517)

0.004

Child-Pugh grade

B vs. A

1.345 (0.756–2.395)

0.313

Tumor number

Multiple vs. Single

1.374 (0.506–3.729)

0.533

Tumor size (cm)

>2 vs. ≦ 2

1.854 (0.819–4.243)

0.138

Histology stages

poor vs. well + moderate

1.143 (0.652–2.004)

0.640

Vascular invasion

Yes vs. No

1.511 (1.046–2.184)

0.028

Statin

Yes vs. No

0.328 (0.190–0.566)

< 0.001

NSAID

Yes vs. No

1.379 (0.606–3.318)

0.443

Aspirin

Yes vs. No

0.689 (0.401–1.184)

0.178

Metformin

Yes vs. No

0.811 (0.508–1.296)

0.381

NA therapy

Yes vs. No

0.670 (0.424–1.057)

0.085

HCV therapy

Yes vs. No

0.963 (0.568–1.634)

0.890