Significance of neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, lymphocyte-to-monocyte ratio and prognostic nutritional index for predicting clinical outcomes in T1–2 rectal cancer

Table 3 Association between inflammation-related parameters and postoperative complications

Classifi-cation	No. of complications	NLR	P value	PLR	P value	LMR	P value	PNI	P value
Classifi-cation	No. of complications	Low (124) /High (30)	P value	Low (84)/ High (70)	P value	Low (59) /High (95)	P value	Low (32) /High (122)	P value
Grade I	2 postop bleed; conservative tx 3 urinary retention; catheterization 2 wound infection; opened at the bedside 2 non-infectious diarrhea; conservative tx	3/6	0.001	2/7	0.097	5/4	0.457	4/5	0.042
Grade II	4 postop bleed; blood transfusion 1 urinary tract infection; antibiotic tx 4 ileus, total parenteral nutrition 2 pneumonia; antibiotic tx 1 diarrhea; antibiotic tx 1 tachyarrhythmia; β-receptor antagonists tx	3/10	< 0.001	6/7	0.525	5/8	1.000	6/7	0.046
Grade I-II	22	6/16	< 0.001	8/14	0.064	10/12	0.457	10/12	0.005
Grade IIIa	2 stricture of the anastomosis; endoscopic dilatation	0/2	0.037	0/2	0.205	2/0	0.145	1/1	0.373
Grade IIIb	1 strangulating intestinal obstruction; reintervention	1/0	1.000	0/1	0.455	1/0	0.386	1/0	0.208
Grade IVa	1 anastomotic leak and postop bleed,; reintervention and intensive care unit	1/0	1.000	1/0	1.000	1/0	0.386	0/1	1.000
Grade III- IVa	4	2/2	0.171	1/3	0.488	4/0	0.040	2/2	0.191
Total	26	8/18	< 0.001	9/17	0.025	14/12	0.074	12/14	< 0.001

NLR neutrophil-to-lymphocyte ratio; PLR platelet-to-lymphocyte ratio; LMR lymphocyte-to-monocyte ratio; PNI prognostic nutritional index; tx treatment

ISSN: 1471-2407