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Table 1 Characteristics of patients with LAPA treated with induction chemotherapy (n = 234)

From: Outcomes of patients with initially locally advanced pancreatic adenocarcinoma who did not benefit from resection: a prospective cohort study

Sex ratio (M/F)

2 (121/103)

 

Mean age (range)

67 (29–89)

 

Performance statusa(%)

 0–1

215 (92)

 

 2–3

19 (8)

 

Mean BMIa(range)

24 (14–42)

 

Weight loss > 5% body weighta(%)

160 (68)

 

Diabetes (%)

15 (36)

 

Back paina(%)

152 (65)

 

Jaundice (%)

136 (84)b

 

CA 19–9 serum levela(UI) (range)

2292 (7–88,300)

 

Tumour location (%)

 Head

161 (69)

 

 Body

57 (24)

 

 Tail

16 (7)

 

Tumour classification (%)

 Borderline

158 (68)

 

 Locally advanced

76 (32)

 

Arterial invasiona(%)

93 (40)

 

Induction regimen (%)

 

 FOLFIRINOX

168 (72)

 

 Gemcitabine

66 (28)

 

Mean number of cycles before restaging (range)

6 (4–8)

 

Explorative laparotomy (%)

45 (19)

 

Treatment after restaging/laparotomy (%) and mean number of cycles (range) after restaging/laparotomy

 FOLFIRINOX

78 (33)

4 (0–18)

 Gemcitabine

30 (12)

4 (0–15)

 Chemoradiation

126 (54)

2 (0–19)

  1. LAPA locally advanced pancreatic adenocarcinoma, BMI body mass index
  2. aat diagnosis
  3. bcalculated for patients with head LAPA