Male | Female | Overall | Sex ratio M/F | ||||
---|---|---|---|---|---|---|---|
n | % | n | % | n | % | ||
Age group (in years) | |||||||
0–14 | 81 | 4.1 | 81 | 4.1 | 162 | 4.1 | 1.0 |
15–24 | 99 | 5.0 | 79 | 4.0 | 178 | 4.5 | 1.3 |
25–39 | 197 | 10.0 | 160 | 8.1 | 357 | 9.1 | 1.2 |
40–64 | 671 | 34.1 | 738 | 37.4 | 1409 | 35.7 | 0.9 |
65–74 | 376 | 19.1 | 379 | 19.2 | 755 | 19.2 | 1.0 |
75 and more | 546 | 27.7 | 535 | 27.1 | 1081 | 27.4 | 1.0 |
Sarcoma topographic groups | |||||||
Soft tissue | 972 | 49.3 | 812 | 41.2 | 1784 | 45.3 | 1.2 |
Bone | 310 | 15.7 | 259 | 13.1 | 569 | 14.4 | 1.2 |
Skin | 262 | 13.3 | 167 | 8.5 | 429 | 10.9 | 1.6 |
Viscera | |||||||
Gastro-intestinal organs | 291 | 14.8 | 287 | 14.6 | 578 | 14.7 | 1.0 |
Female genital organs | – | – | 282 | 14.3 | 282 | 7.2 | – |
Others visceral organs | 102 | 5.2 | 129 | 6.5 | 231 | 5.9 | 0.8 |
Other anatomic sites | 33 | 1.7 | 36 | 1.8 | 69 | 1.8 | 0.9 |
Sarcoma genomic groups | |||||||
Complex genomic alterations | 723 | 36.6 | 847 | 43.0 | 1570 | 39.8 | 0.9 |
MDM2 amplification | 135 | 6.9 | 81 | 4.1 | 216 | 5.5 | 1.7 |
Mutations | 274 | 13.9 | 276 | 14.0 | 550 | 14.0 | 1.0 |
Recurrent translocations | 340 | 17.3 | 438 | 22.2 | 778 | 19.7 | 0.8 |
Undefined/Miscellaneous alterations | 498 | 25.3 | 330 | 16.7 | 828 | 21.0 | 1.5 |
Sarcoma histologic groups | |||||||
Unclassified sarcomaa | 327 | 16.6 | 308 | 15.6 | 635 | 16.1 | 1.1 |
Leiomyosarcoma | 205 | 10.4 | 346 | 17.5 | 551 | 14.0 | 0.6 |
GIST | 246 | 12.5 | 250 | 12.7 | 496 | 12.6 | 1.0 |
Liposarcoma | 228 | 11.6 | 130 | 6.6 | 358 | 9.1 | 1.8 |
Dedifferentiated liposarcoma | 125 | 6.3 | 69 | 3.5 | 194 | 4.9 | 1.8 |
Round cell \ Myxoid liposarcoma | 42 | 2.1 | 29 | 1.5 | 71 | 1.8 | 1.4 |
Pleomorphic liposarcoma | 18 | 0.9 | 7 | 0.4 | 25 | 0.6 | 2.6 |
Liposarcoma NOS | 43 | 2.2 | 25 | 1.3 | 68 | 1.7 | 1.7 |
Chondrosarcoma | 123 | 6.2 | 118 | 6.0 | 241 | 6.1 | 1.0 |
Dermatofibrosarcoma | 101 | 5.1 | 124 | 6.3 | 225 | 5.7 | 0.8 |
Kaposi sarcoma | 156 | 7.9 | 25 | 1.3 | 181 | 4.6 | 6.2 |
Angiosarcoma | 54 | 2.7 | 115 | 5.8 | 169 | 4.3 | 0.5 |
Osteosarcoma | 84 | 4.3 | 71 | 3.6 | 155 | 3.9 | 1.2 |
Ewing sarcoma | 72 | 3.7 | 65 | 3.3 | 137 | 3.5 | 1.1 |
Myxofibrosarcoma | 75 | 3.8 | 49 | 2.5 | 124 | 3.1 | 1.5 |
Rhabdomyosarcoma | 66 | 3.4 | 51 | 2.6 | 117 | 3.0 | 1.3 |
Embryonal rhabdomyosarcoma | 27 | 1.4 | 16 | 0.8 | 43 | 1.1 | 1.7 |
Alveolar rhabdomyosarcoma | 10 | 0.5 | 12 | 0.6 | 22 | 0.6 | 0.8 |
Pleomorphic rhabdomyosarcoma | 14 | 0.7 | 7 | 0.4 | 21 | 0.5 | 2.0 |
Spindle cell rhabdomyosarcoma | 7 | 0.4 | 7 | 0.4 | 14 | 0.4 | 1.0 |
Rhabdomyosarcoma NOS | 8 | 0.4 | 9 | 0.5 | 17 | 0.4 | 0.9 |
Nerve Sheath Tumors | 38 | 1.9 | 44 | 2.2 | 82 | 2.1 | 0.9 |
Endometrial stromal sarcoma | – | – | 81 | 4.1 | 81 | 2.1 | – |
Synovial sarcoma | 37 | 1.9 | 40 | 2.0 | 77 | 2.0 | 0.9 |
Spindle cell synovial sarcoma | 19 | 1.0 | 20 | 1.0 | 39 | 1.0 | 1.0 |
Biphasic synovial sarcoma | 3 | 0.1 | 7 | 0.3 | 10 | 0.2 | 0.4 |
Synovial sarcoma NOS | 15 | 0.8 | 13 | 0.7 | 28 | 0.7 | 1.2 |
Chordoma | 40 | 2.0 | 27 | 1.4 | 67 | 1.7 | 1.5 |
Solitary fibrous tumor, malignant | 33 | 1.7 | 33 | 1.7 | 66 | 1.7 | 1.0 |
Fibrosarcoma | 15 | 0.8 | 16 | 0.8 | 31 | 0.8 | 0.9 |
Malignant myoepithelioma | 12 | 0.6 | 11 | 0.6 | 23 | 0.6 | 1.1 |
Epithelioid haemangioendothelioma | 9 | 0.5 | 11 | 0.6 | 20 | 0.5 | 0.8 |
Other (with fewer than 20 cases) | 49 | 2.5 | 57 | 2.9 | 106 | 2.7 | 0.7 |
Overall | 1970 | 100.0 | 1972 | 100.0 | 3942 | 100.0 | 1.0 |