Fig. 4

Validate Signature genes by Blast with independent cases via the cBioportal database. a Oncoprint table of significant signature genes. Through the cBioPortal Cancer Genomics database, the genes significance (GS) in blue module were explored multidimensional cancer genomics datasets in the context of clinical data and biologic pathways. The Oncoprint table summarizes genomic alterations in all queried genes across samples. Each row represents a gene, and each column represents a tumor sample. Red bars indicate gene amplifications, blue bars are homozygous deletions, and green squares are nonsynonymous mutations. b The summary Mutations table of query genes. The tabular view provides additional information about all mutations in each query genes