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Table 1 BRCA2 and CDKN2A mutations and corresponding variant allele fractions

From: Polyclonal BRCA2 mutations following carboplatin treatment confer resistance to the PARP inhibitor rucaparib in a patient with mCRPC: a case report

GeneProteinCoding changeVariant allele fraction %
BRCA2N1910fs*25727_5728insG83.7
BRCA2A1843_S1985del5528_5956del4290.53
BRCA2A1891_M1936del5671_5808del1380.54
BRCA2D1909_D1911 > EDY5727_5731TAATG > AGACT0.64
BRCA2D1909_E1912 > V5726_5735ATAATGATGA > T0.13
BRCA2I1664_V2049del4989_6146del11580.18
BRCA2I1903_D1909 > M5709_5727TCTTCATAACTCTCTAGAT > G0.11
BRCA2L1908_N1910del5722_5730delCTAGATAAT0.33
BRCA2L1908_S1917del5721_5750del301.8
BRCA2N1766_Q2009del5292_6025 > CA1.3
BRCA2N1910_D1911del5728_5733delAATGAT3.3
BRCA2S1788_P2114 > DTT5362_6340 > GATACCA1.2
BRCA2Unknownsplice site 5333_6841 + 197del17064.8
CDKN2AP114L341C > T10.0