Table 2 Characteristics of studies included in out meta-analysis
Author | Years Included | Region | No. | Treatment Characteristic | Pathology | Depth of Invasion | Staining | Indicator (No.) | Including Statistics | NOS Scores |
|---|---|---|---|---|---|---|---|---|---|---|
Jia (2016) [11] | 2010-2015 | China | 93 | Esophagectomy and lymphadenectomy | SCC/Others | M1-SM3 | NM | LVI(28) | LNM | 5 |
Sepesi (2010) [12] | 2000-2008 | USA | 54 | Esophagectomy and lymphadenectomy | AD | SM | NM | LVI(7) | LNM | 5 |
Leggett (2015) [7] | 1995-2011 | USA | 269 | EMR followed by ablative techniques | AD | LP-SM | H&E | LVI(53) | OS | 6 |
Huh (2017) [13] | 1996-2015 | Korea | 275 | 187 Esophagectomy and 88 ER (Esophagectomy or ER) | SCC | M-SM | H&E | LVI(36) | LNM | 6 |
Zhou (2016) [14] | 2008-2015 | China | 498 | Esophagectomy with lymphadenectomy | SCC | M1-SM3 | H&E/IHC | LI(16/412) | LNM | 7 |
Moon (2014) [15] | 2009-2012 | Korea | 104 | Esophagectomy with lymphadenectomy | SCC | M1-SM3 | H&E | LVI(13) | LNM | 6 |
Mitobe (2013) [16] | 1990-2009 | Japan | 110 | 106 Esophagectomy with lymphadenectomy, 4 esophagectomy follwed ER and lymphadenectomy | SCC | LP-SM3 | IHC | LI(42) | LNM | 6 |
Nentwich (2014) [17] | 1994-2009 | Germany | 67 | Esophagectomy | SCC/AD | SM | NM | LI(16/61) | LNM | 5 |
Raja (2011) [18] | 1983-2010 | USA | 120 | Esophagectomy | SCC/AD | SM | NM | LVI(26) | LNM/OS | 5 |
Nakajima (2002) [19] | 1985-1995 | Japan | 84 | Esophagectomy with lymphadenectomy | SCC | SM | IHC | LI(60) | LNM | 6 |
Choi (2011) [20] | 1991-2009 | Korea | 190 | Esophagectomy with lymphadenectomy | SCC | M1-SM3 | H&E | LVI(39) | LNM | 7 |
Tajima (2000) [21] | 1968-1996 | Japan | 240 | Esophagectomy with lymphadenectomy | SCC | LP-SM | H&E | LI(39/186) | LNM | 6 |
Chiba (2010) [22] | 1992-2008 | Japan | 110 | 107 underwent esophagectomy, 3 patients underwent ER followed esophagectomy | SCC | M-SM | IHC | LI(46) | LNM | 6 |
Yamashina (2013) [8] | 1995-2010 | Japan | 402 | EMR or ESD, some patients received surgery after ER | SCC | EP-SM2 | NM | LVI(33) | OS | 5 |
Xue (2012) [23] | 1990-2004 | China | 271 | Esophagectomy | SCC | M2-SM3 | IHC | LI(51) | LNM | 7 |
Ancona (2008) [24] | 1980-2006 | Italy | 98 | Esophagectomy with lymphadenectomy | SCC/AD | M1-SM3 | NM | LI(34) | LNM | 5 |
Li (2013) [25] | 2006-2011 | China | 189 | Esophagectomy with lymphadenectomy | SCC | M1-SM3 | NM | LVI(22) | LNM | 5 |
Qi (2016) [26] | 2009-2014 | China | 258 | Esophagectomy with lymphadenectomy | SCC | SM | H&E | LVI(18) | LNM/OS | 6 |
Wang (2016) [27] | 2002-2014 | Japan | 598 | Esophagectomy with lymphadenectomy | SCC | M-SM | H&E/IHC | LI(62/228) | LNM | 6 |
Kim (2008) [28] | 1994-2006 | Korea | 200 | Esophagectomy with lymphadenectomy | SCC/AD | M-SM | NM | LI(33) | LNM | 5 |
Tanaka (2014) [9] | 1988-2010 | Japan | 145 | Esophagectomy with lymphadenectomy | SCC | SM1-SM3 | NM | LVI(84) | OS | 5 |
Zhuge (2018) [29] | 2006-2016 | China | 175 | Esophagectomy with lymphadenectomy | SCC | SM1-SM3 | NM | LVI(32) | LNM | 6 |
Xue (2018) [10] | 1990-2004 | China | 199 | Esophagectomy with lymphadenectomy | SCC | M2-SM3 | IHC | LVI(27) | OS | 6 |