Fig. 8

Kaplan-Meier analysis for RFS and OS according to the combined of three protein kinase expression (EGFR, HER4 and EphA3). Upper and lower panels demonstrated the prognostic significantly of the combined of three protein kinase expression or the combined of three protein kinase expression with CA19–9 level on RFS and OS, respectively. 0–1 marker high represented the patients with all markers low or one marker high, 2–3 markers high represented the patients with at least two markers high, others represented three groups of patients (0–1 marker high and CA19–9 low, 0–1 marker high and CA19–9 high or 2–3 markers high and CA19–9 low). p-value less than 0.05 was considered as statistical significance