Predictive value of gamma-glutamyl transpeptidase to lymphocyte count ratio in hepatocellular carcinoma patients with microvascular invasion

Table 1 Clinical and biochemical data of examined patients

Parameter	Non MVI group	MVI group	p value
Parameter	Mean ± SD* (n = 115)	Mean ± SD^a (n = 115)	p value
Sex: female / male (n)	21 / 94	9 / 106	0.019
Age (years)	50.23 ± 12.28	48.34 ± 11.00	0.221
Drinking: absent / present (n)	57 / 58	52 / 63	0.509
Smoking: absent / present (n)	73 / 42	66 / 49	0.345
HBsAg: negative / positive (n)	27 / 88	17 / 98	0.094
HCVAb: negative / positive (n)	109 / 6	113 / 2	0.280
Family history: absent/present (n)	99 / 16	95 / 20	0.468
Tumor number: single/multiple (n)	86 / 29	72 / 43	0.047
Tumor size (cm)	6.08 ± 3.32	8.53 ± 3.78	< 0.001
Liver cirrhosis: absent / present (n)	9 / 106	7 / 108	0.796
NEUT (× 10⁹/L)	3.71 ± 1.50	4.52 ± 2.24	0.001
LYMPH (× 10⁹/L)	1.77 ± 0.61	1.58 ± 0.59	0.012
WBC (× 10⁹/L)	6.17 ± 1.85	6.87 ± 2.50	0.017
Platelets (× 10⁹/L)	172.43 ± 72.73	180.14 ± 82.65	0.453
Albumin (g/L)	41.32 ± 4.01	39.47 ± 4.62	0.002
Globulin (g/L)	29.83 ± 4.79	31.34 ± 6.52	0.045
TBIL (μmol/L)	13.22 ± 4.93	15.07 ± 12.61	0.146
DBIL (μmol/L)	4.47 ± 2.32	5.48 ± 4.10	0.022
ALT (U/L)	37.38 ± 30.49	44.05 ± 33.32	0.115
AST (U/L)	39.33 ± 30.06	55.15 ± 35.29	< 0.001
ALP (U/L)	81.45 ± 87.65	102.22 ± 50.98	0.030
GGT (U/L)	59.17 ± 40.61	114.51 ± 64.46	< 0.001
AFP (ng/ml): median, range	44.60, 1.18–24,200	457.80, 0.61–25,410	0.271
GLR level	38.42 ± 33.52	84.83 ± 61.84	< 0.001

^aData presented as mean ± SD or proportions
n number of patients; HBsAg hepatitis B surface antigen, HCVAb hepatitis C virus antibody, NEUT neutrophil cell count, LYMPH lymphocyte count, WBC white blood cell, TBIL total bilirubin, DBIL direct bilirubin, ALT alanine aminotransferase, AST aspartate aminotransferase, ALP alkaline phosphatase, GGT gamma-glutamyl transpeptidase, AFP alpha-fetoprotein, GLR GGT to lymphocyte ratio

ISSN: 1471-2407