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Table 5 Median Biomarker Concentrations and P-Value Using the Training Set

From: Blood test shows high accuracy in detecting stage I non-small cell lung cancer

BiomarkerNSCLC Median [Q1-Q3], pg/mLAsthma, Smokers, Non-Smokers Median [Q1-Q3], pg/mLP-Value
CA12526.4
[13.7–41.7]
13.6
[6.9–36.7]
0.073
CEA2884.4
[1815.9–5573.8]
2115.3
[1194.8–3242.2]
0.003
CXCL9-MIG4378.2
[2604.0–6844.5]
908.0
[539.0–1965.8]
<  0.001
CYFRA-21-15354.8
[3429.5–8090.4]
5088.3
[2939.9–9770.1]
0.026
GRO2890.0-
[2076.9–4178.0]
874.4
[507.5–1790.2]
<  0.001
HGF869.4
[643.9–1647.1]
476.3
[271.9–1177.1]
0.006
IL-1022.8
[11.7–38.2]
23.8
[14.0–45.8]
0.525
IL-12p7021.1
[15.5–27.0]
19.9
[16.5–127.4]
0.082
IL-16693.6
[345.1–1458.7]
717.5
[298.8–1469.4]
0.902
IL-211.5
[10.9–16.6]
33.8
[19.7–52.1]
0.005
IL-441.7
[25.3–51.6]
33.3
[22.5–50.3]
0.902
IL-517.9
[15.7–23.5]
28.7
[12.8–46.8]
0.188
IL-710.6
[10.6–10.6]
34.9
[18.9–61.1]
NA
IL-8126.3
[44.5–323.8]
23.6
[15.9–42.3]
<  0.001
IL-911.9
[11.0–20.7]
22.3
[15.2–42.6]
0.016
Leptin30,408.0
[16,682.6–45,886.3]
22,190.7
[8684.4–54,863.7]
0.224
LIF45.5
[30.5–79.3]
39.6
[27.1–82.3]
0.511
MCP-1530.2
[391.363–721.512]
372.8
[279.7–462.0]
<  0.001
MIF865.6
[453.6–1501.3]
395.0
[196.7–1274.8]
0.752
MMP-71978.3
[1184.2–3190.33]
3585.2
[2671.9–5080.6]
<  0.001
MMP-993,587.2
[62,827.2–124,300.6]
12,593.8
[8856.8–19,799.6]
<  0.001
MPO353,987.8
[246,376.2–616,739.2]
117,658.8
[69,768.5–212,726.3]
<  0.001
NSE7273.5
[3852.3–10,487.8]
6576.1
[3806.6–46,981.4]
<  0.001
PDGF AB/BB25,169.6
[21,611.8–30,055.0]
41,800.6
[26,115.3–53,016.0]
<  0.001
RANTES105,356.2
[79,497.9–155,040.2]
38,458.4
[23,423.8–112,641.5]
0.003
Resistin35,145.6
[25,185.8–53,466.7]
12,966.2
[9521.2–17,533.1]
<  0.001
SAA6.55e7
[2.52e7–1.2e8]
8.5e6
[4.175e6–1.9825e7]
<  0.001
sCD40L381.8
[155.9–752.5]
219.9
[110.285–628.7]
0.018
sEGFR654.9
[544.0–1175.5]
936.5
[543.2–1943.2]
<  0.001
sFasL229.8
[78.2–498.2]
263.7
[135.9–573.4]
0.03
sICAM-1150,304.6
[123,699.9–187,843.8]
145,329.4
[117,164.7–182,796.7]
0.519
sTNFRII15,477.5
[11,712.9–20,103.6]
5818.1
[4574.8–7295.3]
<  0.001
TNFRI2514.8
[1748.7–3743.5]
619.5
[413.9–860.2]
<  0.001
  1. Table was generated using R Version 3.4.4