Table 3 Univariate and multivariate analysis for overall survival after recurrence

Pathological N stage

<0.001

<0.001

 pN0

1

1

 pN+

1.984(1.438–2.737)

0.507(0.360–0.714)

Pathological TNM stage

<0.001

–

–

 I/II

1

 III

2.353(1.697–3.263)

Salvage treatment

<0.001

<0.001

 SCRT

1

1

 SRT

1.510(1.002–2.276)

0.049

1.419(0.940–2.142)

0.096

 No RT

4.175(2.529–6.891)

<0.001

3.246(1.931–5.458)

<0.001

Site of recurrence

0.002

–

–

 Above the diaphragm

1

 Along with upper abdominal LN recurrence

1.967(1.234–3.136)

0.004

 Along with hematogenous metastases

1.816(1.177–2.804)

0.007

Number of LN recurrence regions

0.042

–

–

 Single region

1

 Multiple regions

1.408(1.012–1.958)