Fig. 1
Tumor volumes (mm3) calculated from external caliper measurements for tumor-bearing mice of both CT26 (a) and 4 T1 model (b). Volumes are described by mean ± SEM (n = 6 mice/group). Irradiation was performed on Day 0. Bottom row presents systematic ADC-results over time in percent compared to baseline (mean ± SEM) for CT26 (c) and 4 T1 tumors (d), respectively. ADC-values are extracted from MRI scans in ROI volume including central part of tumor. *) p < 0.05; **) p < 0.01, ***) p < 0.001: represents the systematic changes in tumor size for each group over time (one-way ANOVA calculations on repeated measurements), and the #) p < 0.05; ##) p < 0.01, ###) p < 0.001 represents differentiation between groups from one-way ANOVA at marked day in figure, e.g. tumor size at Day 4 comparison