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Table 3 CRC cell lines response to the different tested drugs

From: BRAF mutant colorectal cancer: ErbB2 expression levels as predictive factor for the response to combined BRAF/ErbB inhibitors

Cell Line

Venurafenib

Afatinib

Panitumumab

Venurafenib+. Panitumumab

Venurafenib+ Afatinib

SW-48

–

+ (L)

–

–

- +

Colo-205

+

+ (L)

–

+ +

+ + (L)

HT29

+

+ (H)

–

+ −

+ + (H)

  1. Legend: L Low doses of Afatinib (0.01, 0.1, 1 μM), H High dose of Afatinib (10 μM)