Table 2 Univariate analysis
Factor | Responder | Non-responder | p value |
|---|---|---|---|
(N = 108) | (N = 52) | ||
Age > 70 years | 59 (54.6) | 29 (55.8) | 0.8920 |
Female sex | 16 (14.8) | 10 (19.2) | 0.4782 |
ECOG PS score ≥ 2 | 15 (13.9) | 13 (25.0) | 0.0832 |
Stage: IV, recurrence | 81 (75.0) | 46 (88.5) | 0.0487 |
Squamous cell carcinoma | 29 (26.9) | 15 (28.9) | 0.7913 |
Never smoker | 9 (8.3) | 5 (9.6) | 0.7881 |
PD-L1 50–89% | 65 (60.2) | 39 (75.0) | 0.0657 |
Steroid use | 3 (2.8) | 6 (11.5) | 0.0243 |
Metastasis Brain | 14 (13.0) | 12 (23.1) | 0.1043 |
Liver | 12 (11.1) | 8 (15.4) | 0.4439 |
Bone | 28 (25.9) | 14 (26.9) | 0.8932 |
Adrenal | 17 (15.7) | 10 (19.2) | 0.5809 |
Pulmonary | 31 (28.7) | 20 (38.5) | 0.2148 |
Pleural effusion | 17 (15.7) | 19 (36.5) | 0.0032 |
Laboratory data | |||
Neutrophil-to-lymphocyte ratio (< 3) | 30 (27.8) | 14 (26.9) | 0.9097 |
C-reactive protein (< 1.0 mg/dL) | 54 (50.0) | 17 (32.7) | 0.0390 |
Lactate dehydrogenase (< 240 IU/L) | 79 (73.2) | 33 (63.5) | 0.2105 |
Albumin (< 3.5 g/dL) | 47 (43.5) | 26 (50.0) | 0.4407 |