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Table 2 Univariate analysis (10-year Second Tumor-Free Survival)

From: Radiotherapy of prostate cancer: impact of treatment characteristics on the incidence of second tumors

Variables

No. of patients (%)

all sites

pelvis

pelvis/abdomen

STFS

p

STFS

p

STFS

p

Radiotherapy technique

3D-CRT

538 (21.3)

85.8

.627

94.0

.033

92.2

.125

IMRT/VMAT

1988 (78.7)

84.5

89.3

87.5

Prophylactic nodal irradiation

no

1232 (48.8)

88.1

.770

94.4

.092

92.6

.064

yes

1294 (51.2)

84.9

90.6

89.1

Androgen deprivation therapy

no

837 (33.1)

92.8

.999

93.1

.546

92.0

.345

yes

1689 (66.9)

83.8

91.9

89.9

Age, years

≤ 66

688 (27.2)

85.3

.352

90.5

.981

89.6

.374

>  66

1838 (72.8)

86.0

93.5

91.4

Combination of radiotherapy technique and irradiated volumes

3D-CRT without PNI

326 (12.9)

91.0

.887

96.6

.044

95.3

.140

IMRT/VMAT without PNI

906 (35.9)

78.9

89.9

87.8

3D-CRT with PNI

212 (8.4)

85.6

93.7

91.1

IMRT/VMAT with PNI

1082 (42.8)

86.6

87.6

86.3

  1. Legend: 3D-CRT three-dimensional conformal radiotherapy, IMRT Intensity modulated radiotherapy, PNI prophylactic nodal irradiation, STFS second tumor free survival, VMAT volumetric modulated radiotherapy