Fig. 1
From: Simplified molecular classification of lung adenocarcinomas based on EGFR, KRAS, and TP53 mutations
Oncoprint plot of the validation cohort. The mutational profile of the 491 patients in the validation cohort including the 19 most commonly mutated genes is shown. Each column represents a patient. The upper histogram highlights the number of genes mutated in each case. Mutated genes are in descending order of frequency, and their mutation frequency is shown on the y axis. Below the columns, the color map indicates the simplified molecular subtypes. At the bottom, the dot plot shows the age of each patient. The horizontal bars adjacent to the genes illustrate the number and type of genetic alterations. AMP, amplification; InFrameDel, in-frame deletion; NA, sequencing not available