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Table 4 Univariate and multivariate Logistic regression analysis of clinical data and worse postoperative renal function [eGFR≤60 mL/(min × 1.73 m^2)]

From: The effect of renal function change on renal cell carcinoma patients with tumor thrombus after nephrectomy and thrombectomy: a large Chinese center experience

Variables

Univariate analysis

Multivariate analysis

OR

95%CI

P

OR

95%CI

P

Gender (female vs. male)

1.108

0.390–3.147

0.847

   

Age

1

0.962–1.040

0.999

   

Body mass index

0.905

0.804–1.020

0.101

   

ASA classification

 I

–

–

0.437

   

 II

0.25

0.030–2.081

0.2

   

 III

0.25

0.026–2.416

0.231

   

Side (right vs. left)

0.817

0.325–2.050

0.666

   

Tumor diameter

1.088

0.944–1.254

0.247

   

Tumor thrombus grade

 0

–

–

0.232

   

 I

0.24

0.058–0.991

0.049*

   

 II

0.216

0.052–0.898

0.035*

   

 III

0.54

0.077–3.775

0.535

   

 IV

0.42

0.058–3.029

0.389

   

Preoperative serum creatinine

0.966

0.938–0.994

0.019*

–

–

–

Preoperative eGFR

1.054

1.013–1.096

0.009*

1.049

1.009–1.092

0.016*

Operation approach (open vs. laparoscopy)

1.576

0.642–3.864

0.321

   

Ipsilateral adrenalectomy (present vs. absent)

1.492

0.615–3.616

0.376

   

Lymph node dissection (present vs. absent)

0.821

0.339–1.992

0.663

   

Operation time

0.998

0.995–1.002

0.344

   

Pathological type (non-clear cell carcinoma vs. clear cell carcinoma)

2.692

0.570–12.707

0.211

   

WHO/ISUP 2016 Nuclear classification (12vs. 34)

2.277

0.937–5.534

0.069

   

Lymph node metastasis (present vs. absent)

1.134

0.220–5.847

0.881

   

Metastasis (present vs. absent)

2.897

0.789–10.627

0.109

   

Vascular wall invasion (present vs. absent)

0.482

0.195–1.192

0.114

   

Lymphatic vascular invasion (present vs. absent)

1.864

0.573–6.067

0.301

   

Perinephric tissues invasion (present vs. absent)

0.776

0.302–1.991

0.598

   

Renal pelvis invasion (present vs. absent)

1.152

0.378–3.505

0.804

   

Necrosis (present vs. absent)

0.372

0.145–0.956

0.04*

0.384

0.145–1.015

0.054

Sarcomatoid differentiation (present vs. absent)

0.718

0.244–2.114

0.548

   

Postoperative complications (present vs. absent)

0.851

0.352–2.056

0.72

   
  1. eGFR estimated glomerular filtration rate, ISUP International Society of Urological Pathology, ASA American Society of Anesthesiologists; *p<0.05