Table 1 Baseline characteristics of CRC and mCRC patients
Characteristics | CRC patients | mCRC patients |
|---|---|---|
(N = 8136) | (N = 3878) | |
Age at diagnosis, year | ||
 Mean (SD) | 59 (13) | 57 (12) |
 Median (IQR) | 60 (50–68) | 58 (49–66) |
 Min - max | 18–96 | 18–96 |
Age group, n (%) | ||
 18–49 | 1883 (23%) | 1075 (28%) |
 50–59 | 2035 (25%) | 1067 (28%) |
 60+ | 4218 (52%) | 1736 (45%) |
Gender, n (%) | ||
 Female | 3233 (40%) | 1472 (38%) |
 Male | 4903 (60%) | 2406 (62%) |
Department of practice, n (%) | ||
 Internal medicine | 7074 (87%) | 3584 (92%) |
 Surgery | 1062 (13%) | 294 (7.6%) |
Hospital geographic region, n (%) | ||
 North | 489 (6%) | 416 (11%) |
 South | 4972 (61%) | 2258 (58%) |
 East | 533 (6.6%) | 463 (12%) |
 Midwest | 2142 (26%) | 741 (19%) |
Primary tumor size at diagnosis, centimeters | ||
 Missing, n (%) | 2926 (36%) | 2116 (55%) |
 Mean (SD) | 4.48 (2.05) | 4.52 (2.09) |
 Median (IQR) | 4 (3–5.5) | 4 (3–5.5) |
Mutation status, n (%) | ||
 KRAS MUT | 794 (10%) | 525 (14%) |
 KRAS WT | 1246 (15%) | 805 (21%) |
 Unknown | 6096 (75%) | 2548 (66%) |
Primary tumor site at diagnosis, n (%) | ||
 Left-sided | 5751 (71%) | 2659 (69%) |
 Right-sided | 1767 (22%) | 879 (23%) |
 Colorectal NOS | 618 (7.6%) | 340 (8.8%) |
ECOG PS at diagnosis, n (%) | ||
 Missing, n | 2386 | 1470 |
 0 | 724 (12%) | 429 (18%) |
 1 | 4912 (86%) | 1919 (80%) |
 2 | 65 (1.1%) | 51 (2.1%) |
 3 | 11 (0.19%) | 7 (0.29%) |
 4 | 4 (0.07%) | 2 (0.08%) |