Table 3 Treatment related toxicities
Toxicity | Grade 1/2 | Â | Grade 3/4 | Â | ||
|---|---|---|---|---|---|---|
Icotinib (n = 21) | Gefitinib (n = 22) | P value | Icotinib (n = 21) | Gefitinib (n = 22) | P value | |
Rash | 7 (33.3%) | 9 (40.9%) | 0.62 | 1 (4.8%) | 2 (9.1%) | 0.59 |
Pruritus | 5 (23.8%) | 6 (27.3%) | 0.80 | 0 | 0 | Â |
Dizziness | 1 (4.8%) | 2 (9.1%) | 0.59 | 0 | 0 | Â |
Fever | 1 (4.8%) | 1 (4.5%) | 0.97 | 0 | 0 | Â |
Diarrhea | 1 (4.8%) | 3 (13.6%) | 0.33 | 0 | 0 | Â |
Fatigue | 4 (19%) | 3 (13.6%) | 0.64 | 0 | 0 | Â |
Nausea | 6 (28.6%) | 7 (31.8%) | 0.83 | 0 | 0 | Â |
Vomiting | 2 (9.5%) | 5 (22.7%) | 0.25 | 0 | 0 | Â |
Anorexia | 5 (23.8%) | 6 (27.3%) | 0.80 | 0 | 0 | Â |
Raised aminopherase | 3 (14.3%) | 5 (22.7%) | 0.49 | 1 (4.8%) | 0 | 0.31 |
Dyspnea | 3 (14.3%) | 4 (18.2%) | 0.74 | 0 | 0 | Â |
Hemorrhage | 1 (4.8%) | 2 (9.1%) | 0.59 | 0 | 0 | Â |