Fig. 5

Overexpression of MMP7 promotes the tongue cancer cell metastatic potential in vitro. The cell migration and invasion ability were measured by the Transwell assay with or without Matrigel coating (a-b) and wound healing assay (c). a-b, Representative images of the cells that crossed the Transwell chambers containing the control and overexpression groups are presented. Quantification of the results is presented as the mean ± SD (***, P < 0.001). Wound healing assays were performed, and representative images are shown in c (× 40). These experiments were repeated three times independently