Table 3 Factors Associated with Overall Survival by Univariable and Multivariable Analysis
Factors | No. | Univariable Analysis | Multivariable Analysis | ||
|---|---|---|---|---|---|
χ2 | P Value | Hazard Radio | P Value | ||
Age (years) |  | 4.153 | 0.042* | … | … |
 < 65 | 68 |  |  |  |  |
 ≥ 65 | 62 |  |  |  |  |
Gender |  | 0.040 | 0.842 | … | … |
 Male | 100 |  |  |  |  |
 Female | 30 |  |  |  |  |
Differentiation |  | 1.069 | 0.820 | … | … |
 Well/moderately | 54 |  |  |  |  |
 Poorly | 76 |  |  |  |  |
Comorbidities |  | 0.661 | 0.416 | … | … |
 Yes | 76 |  |  |  |  |
 No | 54 |  |  |  |  |
Etiology |  | 0.472 | 0.065 | … | … |
 No | 13 |  |  |  |  |
 HBV | 106 |  |  |  |  |
 HCV | 11 |  |  |  |  |
Cirrhosis |  | 1.293 | 0.728 | … | … |
 Yes | 114 |  |  |  |  |
 No | 16 |  |  |  |  |
Tumor Maximal diameter (cm) |  | 16.466 | < 0.001* | 7.782 (2.942–19.264) | < 0.001* |
 3–5 | 84 |  |  |  |  |
 > 5 | 46 |  |  |  |  |
Tumor volume (ml) |  | 11.275 | 0.001* | … | … |
 ≤ 62.5 | 93 |  |  |  |  |
 > 62.5 | 37 |  |  |  |  |
Tumor number |  | 0.249 | 0.618 | 0.343(0.143–0.836) | 0.003* |
 Single | 71 |  |  |  |  |
 Multiple | 59 |  |  |  |  |
Adjacent major organ |  | 2.801 | 0.278 | … | … |
 Large vessels | 17 |  |  |  |  |
 Diaphragm | 29 |  |  |  |  |
 Gastrointestinal tract | 26 |  |  |  |  |
 No | 58 |  |  |  |  |
Location |  | 1.991 | 0. 370 | … | … |
 Left liver lobe | 25 |  |  |  |  |
 Right liver lobe | 101 |  |  |  |  |
 Left + Right liver lobe | 4 |  |  |  |  |
CTP grade |  | 6.312 | 0.012* | … | … |
 A | 124 |  |  |  |  |
 B | 6 |  |  |  |  |
α-fetoprotein level (ng/ml) |  | 3.176 | 0.075 | … | … |
 > 400 | 64 |  |  |  |  |
 ≤ 400 | 66 |  |  |  |  |
Preoperative TACE |  | 26.433 | <0 .001* | 8.882 (3.698–21.334) | <0 .001* |
 Yes | 29 |  |  |  |  |
 No | 101 |  |  |  |  |
Sessions |  | 0.834 | 0.361 | … | … |
 1 | 110 |  |  |  |  |
 > 1 | 20 |  |  |  |  |
Preoperative planning |  | 0.520 | 0.821 | … | … |
 3D | 66 |  |  |  |  |
 2D | 64 |  |  |  |  |