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Table 5 Multivariate analysis of EFS and OS of MRD-assigned risk and AJS-positive groups in adults

From: Low incidence of ABL-class and JAK-STAT signaling pathway alterations in uniformly treated pediatric and adult B-cell acute lymphoblastic leukemia patients using MRD risk-directed approach – a population-based study

Risk Groups

EFS

OS

 

Hazard Ratio

p-Values

Hazard Ratio

p-Values

SR

reference

–

reference

–

IR

0.885 (0.220–3.570)

0.846

2.219 (0.257–19.136)

0.468

HR + HR-SCT

0.753 (0.146–3.875)

0.734

1.568 (0.134–18.298)

0.720

AJS-positive

5.545 (1.057–29.090)

0.046

2.783 (0.436–17.881)

0.278

  1. SR Standard risk, IR Intermediate risk, HR High risk, HR-SCT High risk–stem cell transplant groups, AJS ABL-class or JAK-STAT pathway fusions, EFS Event-free survival, OS Overall survival, MRD Minimal residual disease
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BMC Cancer

ISSN: 1471-2407

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