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Fig. 1 | BMC Cancer

Fig. 1

From: Low incidence of ABL-class and JAK-STAT signaling pathway alterations in uniformly treated pediatric and adult B-cell acute lymphoblastic leukemia patients using MRD risk-directed approach – a population-based study

Fig. 1

CONSORT diagram of B-ALL study cases. High hyperdiploids, low hypodiploids and cases with no canonical B-ALL alterations, iAMP21 or dic(9;20) were selected for RNA-Seq and FISH (CRLF2 gene break) analysis. After RNA-Seq data analysis, two cases with KMT2A gene rearrangements were excluded. A total of 101 B-ALL patients were screened for non-canonical B-ALL alterations. The number of FLT3-TKD, other JAK-STAT and Ras pathway gene mutations corresponds to the total number of specific alterations in sequenced cases

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BMC Cancer

ISSN: 1471-2407

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