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Table 3 Mean scores depending on sociodemographic and clinical variables

From: Depression, anxiety, fatigue, and quality of life in a large sample of patients suffering from head and neck cancer in comparison with the general population

 

n

PHQ-9

GAD-2

Fatigue

QoL

M

SD

M

SD

M

SD

M

SD

Occupational status

 

p<.001

p=.110

p<.001

p<.001

 Not occupied

625

6.2

6.0

1.34

1.71

47.8

28.5

52.0

21.6

 Occupied

192

5.0

5.3

1.38

1.67

40.7

27.4

59.5

21.8

Alcohol drinking

 

p=.086

p=.139

p<.001

p=.442

 No

602

6.1

5.9

1.40

1.72

48.3

28.4

53.4

21.4

 Yes

215

5.4

5.7

1.20

1.64

40.0

27.7

54.8

21.3

Smoking

 

p=.153

p=.392

p=.319

p=.678

 No

601

5.7

5.7

1.29

1.66

46.7

28.5

53.9

22.2

 Yes

216

6.6

6.3

1.50

1.80

44.8

28.1

53.3

21.1

Tumor group

 

p=.304

p=.943

p=.275

p=.890

 Oral cavity

124

6.3

5.6

1.40

1.70

44.3

28.3

53.2

21.1

 Oropharynx

285

6.3

5.8

1.38

1.75

48.5

27.4

53.2

21.6

 Larynx, Hypopharynx

246

5.9

6.2

1.29

1.68

45.6

29.0

54.2

23.0

 Other

162

6.0

5.9

1.35

1.70

46.2

28.4

53.8

21.9

Tumor stage

 

p=.489

p=.494

p=.067

p=.012

 I

141

5.5

6.1

1.31

1.68

40.9

27.9

58.0

22.5

 II

102

5.5

5.7

1.04

1.40

45.0

29.2

55.4

22.1

 III

122

6.4

6.2

1.47

1.94

46.0

30.7

54.7

24.7

 IV

371

6.2

5.9

1.34

1.65

48.1

27.0

51.3

20.5

Treatment group

 

p=.341

p=.523

p=.015

p=.213

 1: OP + RT - CT-

215

5.5

5.9

1.27

1.67

41.4

28.2

55.8

21.7

 2: OP + RT + CT-

199

5.5

5.6

1.23

1.67

46.0

28.9

54.6

22.3

 3: OP + RT + CT+

246

6.5

5.8

1.53

1.76

48.3

27.4

51.6

20.5

 4: OP - RT + CT+

116

6.1

6.1

1.29

1.63

47.3

28.4

54.2

24.3

 5: Other

41

6.7

6.5

1.41

1.95

55.6

30.2

50.2

20.8

Metastases

 

p=.087

p=.430

p=.054

p=.356

 No

441

5.6

5.9

1.29

1.71

44.4

28.4

54.4

22.8

 Yes

376

6.4

5.9

1.41

1.70

48.3

28.3

53.0

20.8

ECOG performance

 

p<.001

p<.001

p<.001

p<.001

 0

205

3.5

4.4

0.89

1.34

33.8

25.2

62.2

22.0

 1

319

6.5

5.8

1.40

1.61

49.1

26.6

51.0

20.3

 2–4

72

9.8

7.3

2.03

2.16

70.8

23.8

41.8

20.8

Body Mass Index

 

p=.049

p=.0534

p=.002

p<.001

 ≤ 20 kg/m2

135

7.0

6.0

1.52

1.81

52.5

29.4

47.6

22.8

 20 – ≤ 25 kg/m2

391

6.2

6.1

1.39

1.76

47.4

28.0

53.6

21.5

 25 – ≤ 30 kg/m2

216

5.0

5.5

1.16

1.51

40.4

28.3

55.6

21.8

 >  30 kg/m2

75

5.7

5.5

1.35

1.72

45.0

26.3

60.1

20.2

Time since diagnosis

 

p<.001

p=.015

p=.001

p<.001

 ≤ 9 months

429

6.7

6.1

1.50

1.81

49.4

28.1

51.1

20.8

 >  9 months

386

5.1

5.5

1.18

1.57

42.6

28.4

56.7

22.7

  1. OP Surgery, RT Radiotherapy, CT Chemotherapy, p value Significance of the ANOVA with age group and gender as covariates