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Table 3 Mean scores depending on sociodemographic and clinical variables

From: Depression, anxiety, fatigue, and quality of life in a large sample of patients suffering from head and neck cancer in comparison with the general population

  n PHQ-9 GAD-2 Fatigue QoL
M SD M SD M SD M SD
Occupational status   p<.001 p=.110 p<.001 p<.001
 Not occupied 625 6.2 6.0 1.34 1.71 47.8 28.5 52.0 21.6
 Occupied 192 5.0 5.3 1.38 1.67 40.7 27.4 59.5 21.8
Alcohol drinking   p=.086 p=.139 p<.001 p=.442
 No 602 6.1 5.9 1.40 1.72 48.3 28.4 53.4 21.4
 Yes 215 5.4 5.7 1.20 1.64 40.0 27.7 54.8 21.3
Smoking   p=.153 p=.392 p=.319 p=.678
 No 601 5.7 5.7 1.29 1.66 46.7 28.5 53.9 22.2
 Yes 216 6.6 6.3 1.50 1.80 44.8 28.1 53.3 21.1
Tumor group   p=.304 p=.943 p=.275 p=.890
 Oral cavity 124 6.3 5.6 1.40 1.70 44.3 28.3 53.2 21.1
 Oropharynx 285 6.3 5.8 1.38 1.75 48.5 27.4 53.2 21.6
 Larynx, Hypopharynx 246 5.9 6.2 1.29 1.68 45.6 29.0 54.2 23.0
 Other 162 6.0 5.9 1.35 1.70 46.2 28.4 53.8 21.9
Tumor stage   p=.489 p=.494 p=.067 p=.012
 I 141 5.5 6.1 1.31 1.68 40.9 27.9 58.0 22.5
 II 102 5.5 5.7 1.04 1.40 45.0 29.2 55.4 22.1
 III 122 6.4 6.2 1.47 1.94 46.0 30.7 54.7 24.7
 IV 371 6.2 5.9 1.34 1.65 48.1 27.0 51.3 20.5
Treatment group   p=.341 p=.523 p=.015 p=.213
 1: OP + RT - CT- 215 5.5 5.9 1.27 1.67 41.4 28.2 55.8 21.7
 2: OP + RT + CT- 199 5.5 5.6 1.23 1.67 46.0 28.9 54.6 22.3
 3: OP + RT + CT+ 246 6.5 5.8 1.53 1.76 48.3 27.4 51.6 20.5
 4: OP - RT + CT+ 116 6.1 6.1 1.29 1.63 47.3 28.4 54.2 24.3
 5: Other 41 6.7 6.5 1.41 1.95 55.6 30.2 50.2 20.8
Metastases   p=.087 p=.430 p=.054 p=.356
 No 441 5.6 5.9 1.29 1.71 44.4 28.4 54.4 22.8
 Yes 376 6.4 5.9 1.41 1.70 48.3 28.3 53.0 20.8
ECOG performance   p<.001 p<.001 p<.001 p<.001
 0 205 3.5 4.4 0.89 1.34 33.8 25.2 62.2 22.0
 1 319 6.5 5.8 1.40 1.61 49.1 26.6 51.0 20.3
 2–4 72 9.8 7.3 2.03 2.16 70.8 23.8 41.8 20.8
Body Mass Index   p=.049 p=.0534 p=.002 p<.001
 ≤ 20 kg/m2 135 7.0 6.0 1.52 1.81 52.5 29.4 47.6 22.8
 20 – ≤ 25 kg/m2 391 6.2 6.1 1.39 1.76 47.4 28.0 53.6 21.5
 25 – ≤ 30 kg/m2 216 5.0 5.5 1.16 1.51 40.4 28.3 55.6 21.8
 >  30 kg/m2 75 5.7 5.5 1.35 1.72 45.0 26.3 60.1 20.2
Time since diagnosis   p<.001 p=.015 p=.001 p<.001
 ≤ 9 months 429 6.7 6.1 1.50 1.81 49.4 28.1 51.1 20.8
 >  9 months 386 5.1 5.5 1.18 1.57 42.6 28.4 56.7 22.7
  1. OP Surgery, RT Radiotherapy, CT Chemotherapy, p value Significance of the ANOVA with age group and gender as covariates